Eric Dane, 52, revealed in April 2025 that he has amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that impairs muscle function and currently has no cure. In a June 2025 interview with ABC News’ Diane Sawyer, he said he had lost use of his right arm, was enrolled in a research study, and was taking medication aimed at slowing progression, adding that he remained “very hopeful” despite day-to-day challenges.
In late September’s Emmys 2025, Dane missed a planned on-stage reunion after being hospitalized, later explaining the last-minute absence as related to ALS treatment. New photos published October 17–18, 2025, showed him appearing thinner and needing assistance into a wheelchair at Toronto’s airport, prompting fresh concern from fans as he continues working and advocacy around the disease. Together, these updates trace a rapid and public course: disclosure (April), clinical details and trial participation (June), a high-profile setback (September), and visible mobility decline (mid-October).